12 research outputs found

    Energy-efficient embedded machine learning algorithms for smart sensing systems

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    Embedded autonomous electronic systems are required in numerous application domains such as Internet of Things (IoT), wearable devices, and biomedical systems. Embedded electronic systems usually host sensors, and each sensor hosts multiple input channels (e.g., tactile, vision), tightly coupled to the electronic computing unit (ECU). The ECU extracts information by often employing sophisticated methods, e.g., Machine Learning. However, embedding Machine Learning algorithms poses essential challenges in terms of hardware resources and energy consumption because of: 1) the high amount of data to be processed; 2) computationally demanding methods. Leveraging on the trade-off between quality requirements versus computational complexity and time latency could reduce the system complexity without affecting the performance. The objectives of the thesis are to develop: 1) energy-efficient arithmetic circuits outperforming state of the art solutions for embedded machine learning algorithms, 2) an energy-efficient embedded electronic system for the \u201celectronic-skin\u201d (e-skin) application. As such, this thesis exploits two main approaches: Approximate Computing: In recent years, the approximate computing paradigm became a significant major field of research since it is able to enhance the energy efficiency and performance of digital systems. \u201cApproximate Computing\u201d(AC) turned out to be a practical approach to trade accuracy for better power, latency, and size . AC targets error-resilient applications and offers promising benefits by conserving some resources. Usually, approximate results are acceptable for many applications, e.g., tactile data processing,image processing , and data mining ; thus, it is highly recommended to take advantage of energy reduction with minimal variation in performance . In our work, we developed two approximate multipliers: 1) the first one is called \u201cMETA\u201d multiplier and is based on the Error Tolerant Adder (ETA), 2) the second one is called \u201cApproximate Baugh-Wooley(BW)\u201d multiplier where the approximations are implemented in the generation of the partial products. We showed that the proposed approximate arithmetic circuits could achieve a relevant reduction in power consumption and time delay around 80.4% and 24%, respectively, with respect to the exact BW multiplier. Next, to prove the feasibility of AC in real world applications, we explored the approximate multipliers on a case study as the e-skin application. The e-skin application is defined as multiple sensing components, including 1) structural materials, 2) signal processing, 3) data acquisition, and 4) data processing. Particularly, processing the originated data from the e-skin into low or high-level information is the main problem to be addressed by the embedded electronic system. Many studies have shown that Machine Learning is a promising approach in processing tactile data when classifying input touch modalities. In our work, we proposed a methodology for evaluating the behavior of the system when introducing approximate arithmetic circuits in the main stages (i.e., signal and data processing stages) of the system. Based on the proposed methodology, we first implemented the approximate multipliers on the low-pass Finite Impulse Response (FIR) filter in the signal processing stage of the application. We noticed that the FIR filter based on (Approx-BW) outperforms state of the art solutions, while respecting the tradeoff between accuracy and power consumption, with an SNR degradation of 1.39dB. Second, we implemented approximate adders and multipliers respectively into the Coordinate Rotational Digital Computer (CORDIC) and the Singular Value Decomposition (SVD) circuits; since CORDIC and SVD take a significant part of the computationally expensive Machine Learning algorithms employed in tactile data processing. We showed benefits of up to 21% and 19% in power reduction at the cost of less than 5% accuracy loss for CORDIC and SVD circuits when scaling the number of approximated bits. 2) Parallel Computing Platforms (PCP): Exploiting parallel architectures for near-threshold computing based on multi-core clusters is a promising approach to improve the performance of smart sensing systems. In our work, we exploited a novel computing platform embedding a Parallel Ultra Low Power processor (PULP), called \u201cMr. Wolf,\u201d for the implementation of Machine Learning (ML) algorithms for touch modalities classification. First, we tested the ML algorithms at the software level; for RGB images as a case study and tactile dataset, we achieved accuracy respectively equal to 97% and 83.5%. After validating the effectiveness of the ML algorithm at the software level, we performed the on-board classification of two touch modalities, demonstrating the promising use of Mr. Wolf for smart sensing systems. Moreover, we proposed a memory management strategy for storing the needed amount of trained tensors (i.e., 50 trained tensors for each class) in the on-chip memory. We evaluated the execution cycles for Mr. Wolf using a single core, 2 cores, and 3 cores, taking advantage of the benefits of the parallelization. We presented a comparison with the popular low power ARM Cortex-M4F microcontroller employed, usually for battery-operated devices. We showed that the ML algorithm on the proposed platform runs 3.7 times faster than ARM Cortex M4F (STM32F40), consuming only 28 mW. The proposed platform achieves 15 7 better energy efficiency than the classification done on the STM32F40, consuming 81mJ per classification and 150 pJ per operation

    The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

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    Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous research and consensus agreement to improve disease definition and classification. An International League Against Epilepsy (ILAE) Task Force (TF) reviewed the FCD classification of 2011 to identify existing gaps and provide a timely update. The following methodology was applied to achieve this goal: a survey of published literature indexed with ((Focal Cortical Dysplasia) AND (epilepsy)) between 01/01/2012 and 06/30/2021 (n = 1349) in PubMed identified the knowledge gained since 2012 and new developments in the field. An online survey consulted the ILAE community about the current use of the FCD classification scheme with 367 people answering. The TF performed an iterative clinico-pathological and genetic agreement study to objectively measure the diagnostic gap in blood/brain samples from 22 patients suspicious for FCD and submitted to epilepsy surgery. The literature confirmed new molecular-genetic characterizations involving the mechanistic Target Of Rapamycin (mTOR) pathway in FCD type II (FCDII), and SLC35A2 in mild malformations of cortical development (mMCDs) with oligodendroglial hyperplasia (MOGHE). The electro-clinical-imaging phenotypes and surgical outcomes were better defined and validated for FCDII. Little new information was acquired on clinical, histopathological, or genetic characteristics of FCD type I (FCDI) and FCD type III (FCDIII). The survey identified mMCDs, FCDI, and genetic characterization as fields for improvement in an updated classification. Our iterative clinico-pathological and genetic agreement study confirmed the importance of immunohistochemical staining, neuroimaging, and genetic tests to improve the diagnostic yield. The TF proposes to include mMCDs, MOGHE, and “no definite FCD on histopathology” as new categories in the updated FCD classification. The histopathological classification can be further augmented by advanced neuroimaging and genetic studies to comprehensively diagnose FCD subtypes; these different levels should then be integrated into a multi-layered diagnostic scheme. This update may help to foster multidisciplinary efforts toward a better understanding of FCD and the development of novel targeted treatment options

    Approximate Computing Circuits for Embedded Tactile Data Processing

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    In this paper, we demonstrate the feasibility and efficiency of approximate computing techniques (ACTs) in the embedded Support Vector Machine (SVM) tensorial kernel circuit implementation in tactile sensing systems. Improving the performance of the embedded SVM in terms of power, area, and delay can be achieved by implementing approximate multipliers in the SVD. Singular Value Decomposition (SVD) is the main computational bottleneck of the tensorial kernel approach; since digital multipliers are extensively used in SVD implementation, we aim to optimize the implementation of the multiplier circuit. We present the implementation of the approximate SVD circuit based on the Approximate Baugh-Wooley (Approx-BW) multiplier. The approximate SVD achieves an energy consumption reduction of up to 16% at the cost of a Mean Relative Error decrease (MRE) of less than 5%. We assess the impact of the approximate SVD on the accuracy of the classification; showing that approximate SVD increases the Error rate (Err) within a range of one to eight percent. Besides, we propose a hybrid evaluation test approach that consists of implementing three different approximate SVD circuits having different numbers of approximated Least Significant Bits (LSBs). The results show that energy consumption is reduced by more than five percent with the same accuracy loss

    Low power approximate multipliers for energy efficient data processing

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    Computation accuracy can be adequately tuned on the specific application requirements in order to reduce power consumption. To give some examples, image processing and audio/speech recognition e.g., multimedia applications may provide more accurate outputs than human capabilities can appreciate. In this case, producing inexact numerical outputs can be acceptable and approximate computing circuits could be employed to reduce power consumption by decreasing the hardware complexity. This paper proposes approximate multipliers based on exact and inexact adder circuits and their FPGA implementation: the proposed multipliers can be applied for both signed and unsigned operations. Two scenarios were considered and analyzed in this paper. First, the performance of the proposed multiplier based on inexact adder is evaluated by comparing the power consumption, the accuracy of computation, and the time delay with those of an approximate multiplier based on exact adder. Second, the design parameters of the proposed multipliers are compared with those of the Baugh-Wooley multiplier. On the other hand, we analyzed and compared the performance of the unsigned approximate multipliers with respect to the signed approximate ones. Results prove that the proposed approximate multipliers achieve a reduction in power consumption of 56.3% with respect to the Baugh-Wooley multiplier at cost of less than 5% of accuracy loss

    The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

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    Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous research and consensus agreement to improve disease definition and classification. An International League Against Epilepsy (ILAE) Task Force (TF) reviewed the FCD classification of 2011 to identify existing gaps and provide a timely update. The following methodology was applied to achieve this goal: a survey of published literature indexed with ((Focal Cortical Dysplasia) AND (epilepsy)) between 01/01/2012 and 06/30/2021 (n = 1349) in PubMed identified the knowledge gained since 2012 and new developments in the field. An online survey consulted the ILAE community about the current use of the FCD classification scheme with 367 people answering. The TF performed an iterative clinico-pathological and genetic agreement study to objectively measure the diagnostic gap in blood/brain samples from 22 patients suspicious for FCD and submitted to epilepsy surgery. The literature confirmed new molecular-genetic characterizations involving the mechanistic Target Of Rapamycin (mTOR) pathway in FCD type II (FCDII), and SLC35A2 in mild malformations of cortical development (mMCDs) with oligodendroglial hyperplasia (MOGHE). The electro-clinical-imaging phenotypes and surgical outcomes were better defined and validated for FCDII. Little new information was acquired on clinical, histopathological, or genetic characteristics of FCD type I (FCDI) and FCD type III (FCDIII). The survey identified mMCDs, FCDI, and genetic characterization as fields for improvement in an updated classification. Our iterative clinico-pathological and genetic agreement study confirmed the importance of immunohistochemical staining, neuroimaging, and genetic tests to improve the diagnostic yield. The TF proposes to include mMCDs, MOGHE, and “no definite FCD on histopathology” as new categories in the updated FCD classification. The histopathological classification can be further augmented by advanced neuroimaging and genetic studies to comprehensively diagnose FCD subtypes; these different levels should then be integrated into a multi-layered diagnostic scheme. This update may help to foster multidisciplinary efforts toward a better understanding of FCD and the development of novel targeted treatment options

    CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease

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    Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element Vtb\bf V_{tb}

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    We present the final combination of CDF and D0 measurements of cross sections for single-top-quark production in proton-antiproton collisions at a center-of-mass energy of 1.96 TeV. The data correspond to total integrated luminosities of up to 9.7 fb−1^{−1} per experiment. The t-channel cross section is measured to be σt_t=2.25−0.31+0.29_{-0.31}^{+0.29} pb. We also present the combinations of the two-dimensional measurements of the s- vs t-channel cross section. In addition, we give the combination of the s+t channel cross section measurement resulting in σs+t_{s+t}=3.30−0.40+0.52_{-0.40}^{+0.52} pb, without assuming the standard model value for the ratio σs_s/σt_t. The resulting value of the magnitude of the top-to-bottom quark coupling is |Vtb_{tb}|=1.02−0.05+0.06_{-0.05}^{+0.06}, corresponding to |Vtb_{tb}|>0.92 at the 95% C.L
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